bispecificantibody相关论文
Bispecific antibody simultaneously targeting PD1 and HER2 inhibits tumor growth via direct tumor cel
Immune checkpoint blockade has shown significant clinical benefit in multiple cancer indications,but many patients are e......
Anti-CD3×EGFR bispecific antibody redirects cytokine-induced killer cells to glioblastoma in vitro a
The epidermal growth factor receptor(EGFR)is an attractive target for immunotherapy of EGFR+tumors....
Selecting an ideal molecular format from diverse structures is a major challenge in developing a bispecific antibody(BsA......
将诱变的αＣＤ３杂交瘤（ＴＫ~－）与ＰＤ４杂交瘤（ＨＧＰＲＴ~－）融合，获得分泌双功能抗体（ＢｓＡｂ）的四体杂交瘤Ｃ３．ＢｓＡｂＣ３可分别与ＣＤ３分子及胃癌相关抗原Ｐ４０反应．体外杀伤试验证实，当效靶比为４０：１，ＢｓＡｂＣ３浓度......
应用无筛选标记细胞株杂交瘤．杂交瘤细胞直接融合法制备了２株分泌抗慢性Ｂ淋巴细胞白血病（Ｂ－ＣＬＬ）Ｉｄｘ抗ＣＤ３双特异性抗体（ＢｓＡｂ）的四价体瘤细胞株。采用间接ＥＬＩＳＡ试......
目的制备抗人CD3-抗人IgMμ链双特异性抗体(Bispecific antibody,BsAb)的细胞株,并对建株的杂交-杂交瘤的稳定性及活性进行鉴定.方......
